BGC > Produktsuche > 6-Chloro-5-(4-(1-hydroxycyclobutyl)phenyl)-1H-indole-3-carboxylic acid | 1467057-23-3

Molecular Formula: C19H16ClNO3
Molecular Weight: 341.78824

Description:
PF 06409577 is a potent and selective allosteric activator of AMPK (EC50 values are 7 and >40000 nM for AMPKα1β1γ1 and AMPKα1β2γ1, respectively) for the potential treatment of diabetic nephropathy. PF-06409577 showed efficacy in a preclinical model of diabetic nephropathy.

• Molecular Weight:341.79
• Purity:≥98% by HPLC

Molecular Formula:
C19H16ClNO3
Canonical SMILES:
C1CC(C1)(C2=CC=C(C=C2)C3=C(C=C4C(=C3)C(=CN4)C(=O)O)Cl)O
InChI:
InChI=1S/C19H16ClNO3/c20-16-9-17-14(15(10-21-17)18(22)23)8-13(16)11-2-4-12(5-3-11)19(24)6-1-7-19/h2-5,8-10,21,24H,1,6-7H2,(H,22,23)
InChIKey:
FHQXLWCFSUSXBF-UHFFFAOYSA-N
Storage: Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms:
PF-06409577; PF06409577; PF-6409577; PF6409577; PF 6409577